nematode and water bear

Publications

Tenlen, J.R.(2018). Microinjection of dsRNA in tardigrades. Cold Spring Harbor Protocols. http://dx.doi.org/10.1101/pdb.prot102368.

Boothby, T.C., Tenlen, J.R., Smith, F.W., Wang, J.R., Patanella, K.A., Nishimura, E.O., Tintori, S.C., Li, Q., Jones, C.D., Yandell, M., Messina, D.N., Glasscock, J., Goldstein, B. (2015). Evidence for extensive horizontal gene transfer from the draft genome of a tardigrade. Proc Natl Acad Sci USA 112, 15976-81. [Manuscript (PubMed)]

Tenlen, J.R., McCaskill, S. and Goldstein, B. (2013). RNA interference can be used to disrupt gene function in tardigrades. Development Genes Evolution 223, 171-181. [Manuscript (PubMed)] Access the recommendation on F1000 Prime

Tenlen, J.R., Molk, J.N., London, N.L., Page, B.D. and Priess, J.R. (2008). MEX-5 asymmetry in 1-cell C. elegans embryos requires PAR-4- and PAR-1-dependent phosphorylation. Development 135, 3665-3675. [PubMed] Access the recommendation on F1000 Prime

Rasmussen, J.P., English, K., Tenlen, J.R. and Priess, J.R. (2008). Notch signaling and morphogenesis of single-cell tubes in the C. elegans digestive tract. Developmental Cell 14, 559-569. [PubMed]

Le, T.N., Blomstedt, C.K., Kuang, J., Tenlen, J., Gaff, D.F., Hamill, J.D. and Neale, A.D. (2007). Desiccation-intolerance specific gene expression in leaf tissue of the resurrection plant Sporobolus stapfianus. Functional Plant Biology 34, 589-600.

Page, B.D., Diede, S.J., Tenlen, J.R., and Ferguson, E.L. (2007). EEL-1, a Hect E3 ubiquitin ligase, controls asymmetry and persistence of the SKN-1 transcription factor in the early C. elegans embryo. Development 134, 2303-2314. [PubMed]

Tenlen, J.R.*, Schisa, J.A.*, Diede, S.J. and Page, B.D. (2006). Reduced dosage of pos-1 suppresses Mex mutants and reveals complex interactions among CCCH zinc-finger proteins during Caenorhabditis elegans embryogenesis. Genetics 174, 1933-1945. *These authors contributed equally to this work. [PubMed]

Park, F.D., Tenlen, J.R. and Priess, J.R. (2004). C. elegans MOM-5/Frizzled functions in MOM-2/Wnt-independent cell polarity and is localized asymmetrically prior to cell division. Current Biology 14, 2252-2258. [PubMed]

Other Writings

The Faculty Perspective - Scientific Reading for Non-Scientists - a post I wrote for the SPU Reads blog (November 2014)

Apply to Grad School (Life Sciences) - an article I wrote for the SPU Biology Department website.

Navigating college as a first-generation student - an essay I wrote about my experiences as a first-generation college student, as part of SPU's participation in the inaugural National First-Generation College Celebration (Nov. 8, 2019).

Presentations

November 4, 2019: The Science Squad Lecture Series - the Science Squad is dedicated to promote STEM careers among high school students, in part by inviting researchers from diverse fields to present their research. My full presentation and a special animated version (with animation by Science Squad intern Rachel Hu) are now available on YouTube.

Media interviews

August 2019: Interviewed by the "Afternoons with Rob Breakenridge" program on Global News Radio, Calgary, Alberta (770 CHQR). The interview was in response to the news about the crash landing of a lunar lander on the moon, which carried (among many other things), dehydrated tardigrades.

March 2019: Quoted in the article "After Conquering Space, Water Bears Could Save the Global Vaccine and Blood Supply”, by Sukee Bennett (NOVA Next). The article describes research by Dr. Thomas Boothby and others to utilize tardigrade stress-response proteins as a way to transport drugs and proteins in sub-optimal conditions.

November 2016: Quoted in the article "Water bear genomes start to reveal hardy critter’s secrets", by Ryan Cross (Chemical & Engineering News, 94(44): 20-21). The article describes a recent discovery of the Dsup protein in tardigrades by the Kunieda lab. This protein is being explored for its role in protecting tardigrade chromosomes from damage.